Omnics in the United Kingdom are treated as second-class citizens, forced to undergo mandatory registration, and denied basic rights and citizenship. As a result, the extremist Null Sector organization enjoyed popular support and took more and more control of London.
Seven years before the present day, the King's Row Uprising saw London in flames. By the 27th day of the Uprising, Null Sector had taken Mayor Nandah, Mondatta, and a hundred other captives and held them hostage in an armed power plant. Thousands were in need of medical aid. The prime minister of the UK forbade Overwatch from interfering. Despite this, Jack Morrison authorized an illegal Overwatch operation to end the situation.
In the present day, the city remains a hotbed of human-omnic conflict.